Research is integral to a career in immuno-oncology and serves as the cornerstone of the fellowship experience. During the first several months of fellowship, the fellows will concentrate their efforts on didactics, and will meet individually with investigators to gain exposure across the wide repertoire of research being conducted at Earle A. Chiles Research Institute.
By the end of the second month with the help of faculty, the fellow is expected formulate a research project in immuno-oncology. Several potential clinical translational projects will be offered by faculty, but development of independent ideas is also encouraged. It is also encouraged that the IO fellows begin discernment and meet with selected faculty before their fellowship begins to facilitate project selection. The overarching goal is for the fellow to gain hands-on exposure across clinical trials development, biomarkers development and literature review of immunotherapy trends.
The research projects ideally should be cohesive and thematic, allowing for the fellow to develop in-depth knowledge and research direction in a particular area of investigation, which they may continue to pursue following the completion of the immuno-oncology fellowship.
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Fellows will receive intensive didactic training in the principles of immuno-oncology, taught by leaders in the field across a variety of domains, including clinical immuno-oncology, translational/basic immunology and clinical trials management/nursing. For the one-on-one didactic period, fellows will receive interactive but formalized lectures on the topic and will also discuss key points highlighted by the reading materials.
In addition to the didactic curriculum, each unit will be accompanied by practicums consisting of “on the job” immersion experiences that allow for consolidation of knowledge. The nature and quantity of practicums will depend on the interest of the fellow, however at least one practicum for each unit will be required.
All fellows are encouraged to spend one half-day in the medical oncology clinic, which will help to contextualize the curriculum in a “real-world” environment. Fellows will first rotate across several tumor-specific clinics (i.e. lung, breast, heme, melanoma), then subsequently at their discretion may focus on one or several tumor types. They will also rotate on inpatient adoptive cellular therapy, experimental therapeutics and high-dose IL-2/transplant service, or in observerships with surgical oncology or radiation oncology.
Every Friday between 8am – 9am, fellows will participate in the Earle A. Chiles Research Institute lab meetings, in which scientists and guest speakers present original research pertaining to a variety of immuno-oncology topics.
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